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Recently Discovered Human Coronaviruses

Identifieur interne : 002A41 ( Main/Exploration ); précédent : 002A40; suivant : 002A42

Recently Discovered Human Coronaviruses

Auteurs : Brigitte A. Wevers [Pays-Bas] ; Lia Van Der Hoek [Pays-Bas]

Source :

RBID : PMC:7131583

Descripteurs français

English descriptors

Abstract

In marked contrast to their historical classification as relatively harmless, common cold-causing, respiratory pathogens, human coronaviruses (HCoVs) are associated with more severe clinical complications, as emphasized by the discovery of severe acute respiratory syndrome-associated CoV (SARS-CoV) in 2003. Still, their precise pathogenic potential is largely unknown, particularly regarding the most recently identified strains HCoV-NL63 and HCoV-HKU1, and definite proof for their etiology remains a major challenge. This article focuses on the characteristics of the five HCoVs that are known, and summarizes current knowledge of their pathogenic potential in people, with an emphasis on the interactions between these viruses and their cognate receptors on susceptible target cells.


Url:
DOI: 10.1016/j.cll.2009.07.007
PubMed: 19892230
PubMed Central: 7131583


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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</country>
<region>
<li>Hollande-Septentrionale</li>
</region>
<settlement>
<li>Amsterdam</li>
</settlement>
</list>
<tree>
<country name="Pays-Bas">
<region name="Hollande-Septentrionale">
<name sortKey="Wevers, Brigitte A" sort="Wevers, Brigitte A" uniqKey="Wevers B" first="Brigitte A." last="Wevers">Brigitte A. Wevers</name>
</region>
<name sortKey="Van Der Hoek, Lia" sort="Van Der Hoek, Lia" uniqKey="Van Der Hoek L" first="Lia" last="Van Der Hoek">Lia Van Der Hoek</name>
</country>
</tree>
</affiliations>
</record>

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